Bomi Lee

Bomi Lee, PhD, Assistant Professor, Department of Pediatrics -Gastroenterology, Stanford University School of Medicine 

Research Description: Dr. Lee’s lab focuses on understanding the local and systemic immunopathogenic landscapes and mechanisms of pancreatitis. Her previous research has uncovered distinct immune responses and signals associated with various etiologies (hereditary versus idiopathic) and states (acute, recurrent acute, and chronic) of pancreatitis. Dr. Lee and her lab continue to investigate immune mechanisms and decode pathogenic immune signals by utilizing advanced technologies and innovative experimental and genetic animal models, with the aim of identifying therapeutic targets for different types and causes of pancreatitis. Recently, her research has expanded to include pancreatitis-related complications and diseases, such as osteopathy, type 3c diabetes, and pancreatic cancer, through established intramural and extramural collaborations. The goal of Dr. Lee’s lab is to identify early biomarkers and target molecules that can aid in prognosis, prevention, and treatment of pancreatitis and its complications, ultimately benefiting patients.

Dr. Lee has been actively collaborating with BaaS as a part of the SDRC research core facilities, and she and her team are interested in working with other cores, such as Diabetes Immune Monitoring Core and Diabetes Genomics and Analysis Core.

Selected relevant publications (Stanford DRC members are in BOLD)

1. Lee B, Adamska JZ, Namkoong H, Bellin MD, Wilhelm J, Szot GL, Louis DM, Davis MM, Pandol SJ, Habtezion A. Distinct immune characteristics distinguish hereditary and idiopathic chronic pancreatitis. J Clin Invest. 2020;130(5):2705-11. Epub 2020/02/14. doi: 10.1172/JCI134066. PubMed PMID: 32053120; PMCID: PMC7190911.

2. Lee B, Namkoong H, Yang Y, Huang H, Heller D, Szot GL, Davis MM, Husain SZ, Pandol SJ, Bellin MD, Habtezion A. Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis. Gut. 2022;71(9):1831-42. Epub 2021/10/28. doi: 10.1136/gutjnl-2021-324546. PubMed PMID: 34702715; PMCID: PMC9105403.

3. Lee B, Jones EK, Manohar M, Li L, Yadav D, Conwell DL, Hart PA, Vege SS, Fogel EL, Serrano J, Andersen D, Bellin MD, Topazian MD, Van Den Eeden SK, Pandol SJ, Forsmark CE, Fisher WE, Park WG, Husain SZ, Habtezion A, Consortium for the Study of Chronic Pancreatitis D, Pancreatic C. Distinct Serum Immune Profiles Define the Spectrum of Acute and Chronic Pancreatitis From the Multicenter Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies (PROCEED) Study. Gastroenterology. 2023. Epub 2023/04/16. doi: 10.1053/j.gastro.2023.03.236. PubMed PMID: 37061168.